Transforming Human
Health & Aging
Using worms.
We develop novel therapeutics derived from symbiotic organisms that modulate inflammation, metabolism, and tissue regeneration- core pathways that underlie chronic disease, resilience, and aging.
Read moreabout our workOverview
Our mission is to restore missing components of the human molecular legacy.
Our mission is to restore what has been lost. The removal of intestinal worm- longtime partners in our evolution- has disrupted our gut biome and contributed to modern immune-related diseases.
We aim to return their beneficial components, without reintroducing live worms, to bring relief to millions. The name Holoclara comes from the Greek holokleros, meaning "complete."
Discover Engine
We develop drugs from organisms that rely on tuning multiple networks simultaneously.
This is the longest running drug development program in human history.
Learn moreLeadership & Governance
Leadership & Governance
ANDREA CHOE
CEO / CO-FOUNDER
ANDREA CHOE
CEO / CO-FOUNDER
BRIAN VARNUM
HEAD OF RESEARCH & DEVELOPMENT
BRIAN VARNUM
HEAD OF RESEARCH & DEVELOPMENT
HUNG NGUYEN
VP PRECLINICAL DEVELOPMENT
HUNG NGUYEN
VP PRECLINICAL DEVELOPMENT
Hung is the VP of Preclinical Development at Holoclara. He brings more than 28 years of drug development expertise from research to clinic, including 18 years at Amgen. He received his PhD from the University of Pennsylvania.
OLIVER LOSÓN
VP BUSINESS OPERATIONS
OLIVER LOSÓN
VP BUSINESS OPERATIONS
Oliver brings a diverse range of leadership skills to Holoclara, having previously overseen IP, licensing, and entrepreneurship at Caltech’s Office of Technology Transfer. He also managed R&D and business operations at 1200 Pharma, where he was part of the founding team.
MARIANA UCHOA
DIRECTOR OF IMMUNOLOGY
MARIANA UCHOA
DIRECTOR OF IMMUNOLOGY
Mariana received her PhD at USC, where her doctoral work focused on innate immune tolerance. Mari brings her immunology leadership expertise to Holoclara, with previous experience building and leading an R&D team in autoimmune therapy.
NICK EVERETTS
COMPUTATIONAL BIOLOGIST
NICK EVERETTS
COMPUTATIONAL BIOLOGIST
Nick is a Scientist at Holoclara with a focus on computational biology. He completed his postdoctoral work at UC Berkeley, using single cell transcriptomics to characterize novel interactions during organogenesis and tissue regeneration. He received his PhD at UC Berkeley.
Alice Kwon
PRINCIPAL SCIENTIST
Alice Kwon
PRINCIPAL SCIENTIST
WINNIE TAI-FERRER
SR. RESEARCH ASSOCIATE
WINNIE TAI-FERRER
SR. RESEARCH ASSOCIATE
Winnie is a Senior Research Associate at Holoclara, with a focus on in vivo and in vitro immunology assay development. She brings more than 20 years of experience in the life science industry. She received her BS at UCLA.
BIOLA FATUSIN
RESEARCH ASSOCIATE
BIOLA FATUSIN
RESEARCH ASSOCIATE
Biola is a Research Associate at Holoclara. She received her Bachelors of Science from Chapman University, where her laboratory research focused on microbiology and immunology. Following her graduation, she worked at Zymo Research.
SARAH TORRES
EXECUTIVE ASSISTANT
SARAH TORRES
EXECUTIVE ASSISTANT
Sarah is the Executive Assistant to the CEO. She has extensive experience in administration and lab management in the life science research space, which includes 17 years at Caltech and City of Hope.